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In order to properly develop from simple sets of pluripotent cells, organisms need to establish organs. Among the numerous multiscale processes taking place over development, we nowadays know that "symmetry breaking" in early embryo development is achieved by the formation of patterns of proteins, that is the establishment of non-uniform concentrations of proteins across tissues.

In my work, I develop mathematical models to unveil the complex molecular networks leading to organ formation as well as their dynamical and stochastic properties.

Related publications:

  • S. Grigolon et al., J. R. Soc., 2015 [PDF]

  • S. Grigolon, Ithaca, 2021 (in italian) [PDF]

  • S. Grigolon et al., in preparation

Laboratoire Jean Perrin (UMR 8237)

Towers 32-33

Office 524

Sorbonne Univeristé & CNRS

4 Place Jussieu 

75252 Paris CEDEX 05

France

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© by Silvia Grigolon, 2023

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