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The advent of highthroughput sequencing techniques has allowed the collection of a huge amount of data within cells, from the genome to the protein scale. One of the recent intuition is that of using the statistics embedded in these datasets to extract the underlying complex networks regulating the interactions, thus the dynamics, among the different constituents of the system. 

In my past work, I have applied this idea to identify protein functional sites from protein sequences. Among my future directions, I would like to extend this to the analysis of other type of "large biological datasets".

Related publications:

  • S. Grigolon et al., Mol. Biosyst., 2016 [PDF]

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